NAD+: The molecule of longevity — what it is, how you grow it naturally and the link to intermittent fasting

1. Introduction — What is NAD+ and why everyone talks about it

In recent years, in health and anti-aging circles, a term appears more and more often: OVER+. It is the abbreviation of Nicotinamide Adenine Dinucleotide, an essential molecule present in every cell of your body.

If energy in the body were a currency, NAD+ would be central bankWithout it, energy transactions cannot be made.

The roles of NAD+ include:

• Energy Production (ATP) in Mitochondria
• DNA repair
• Activation of longevity genes (sirtuins)
• Regulation of metabolism and inflammation

The problem? NAD+ Levels Decrease as We Age— sometimes more than 50% by the age of 50. This decrease is associated with fatigue, accelerated cellular aging, and a reduced ability to repair tissues.

2. How NAD+ works in the body

NAD+ exists in two forms:

• OVER+— oxidized form, active in biochemical reactions
• NADH— reduced form, which carries electrons

The two forms transform into each other in the reactions Redox(reduction-oxidation), essential for metabolism.

NAD+ activates sirtuins (SIRT1—SIRT7), some “guardian” proteins that protect DNA, reduce inflammation, and stimulate cell repair.

Also, NAD+ is a cofactor for PARP Enzymes responsible for repairing breaks in DNA.

Without NAD+, mitochondria Cell power plants cannot produce energy efficiently.

3. The Link Between NAD+ and Intermittent Fasting

Intermittent fastingIt's not just a way to control calories. It is a way that you stimulate internal repair mechanisms, including increasing NAD+ levels.

Here's how:

• Decreases insulin and glucose, which increases the NAD+/NADH ratio.
• Activating SIRT1, which improves DNA repair.
• Grows mitochondrial biogenesis(creation of new mitochondria).
• It stimulates autophagy— the process by which cells recycle defective components.

Studies show that regular periods of fasting can increase NAD+ levels, which means more energy, a clearer mental state and a slower aging process.

4. Natural sources of NAD+ and precursors

There are foods that contain NAD+ precursors, that is, substances that the body can convert into NAD+. Among the most important are niacin (Vitamin B3), tryptophanand nicotinamide riboside (NR).

Obviously, the effect is stronger when combined with intermittent fasting and exercise.

Table of natural sources of NAD+:

5. Other ways to increase NAD+ (besides diet)

1. Flashing post— mentioned above, it is one of the most effective natural methods.
2. Physical exercise— HIIT workouts and resistance training increase the NAD+/NADH ratio.
3. Exposure to coldIce baths or cold showers stimulate NAD+ production.
4. Reducing alcohol consumptionAlcohol depletes NAD+ in the process of metabolism.
5. Supplements— nicotinamide riboside (NR), nicotinamide mononucleotide (NMN), niacin.

6. When you should think about supplementation

NAD+ deficiency is not commonly diagnosed, but can be suspected if:

• You have chronic fatigue
• Recovery after exercise is slow
• You have concentration and memory problems
• Signs of premature aging appear

People over the age of 40, those with metabolic diseases or with increased oxidative stress can benefit from supplementation.

Doses should be determined with a doctor, because an excess of niacin can cause adverse effects.

7. Practical conclusion

NAD+ is not just “another vitamin” — it is a central molecule for life, energy and longevity.

Increasing NAD+ levels by intermittent post, diet rich in precursors and exercise is a natural strategy, simple and accessible to anyone.

Do you want to lower your inflammation and increase your natural energy?

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